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GPR35 has not been detected as a mutational cancer driver

GPR35
Ensembl id ENSG00000178623
Mutated samples
Coding Sequence 32 (0.5%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GPR35 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 3 0.81
Uterine corpus endometrioid carcinoma No 2 2 0.87
Small cell lung carcinoma No 2 2 2.90
Breast carcinoma No 4 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Pancreas adenocarcinoma No 2 1 0.47
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 3 1 0.62
Glioblastoma multiforme No 2 1 0.26
Lung adenocarcinoma No 3 0 0.00
Bladder carcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence