Top
GPR17 has not been detected as a mutational cancer driver

GPR17
Ensembl id ENSG00000144230
Mutated samples
Coding Sequence 54 (0.8%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GPR17 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 5 4 2.30
Bladder carcinoma No 4 3 3.06
Lung adenocarcinoma No 5 2 0.51
Breast carcinoma No 3 2 0.17
Cutaneous melanoma No 10 2 0.54
Uterine corpus endometrioid carcinoma No 4 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Prostate adenocarcinoma No 2 1 0.41
Renal clear cell carcinoma No 2 1 0.24
Small cell lung carcinoma No 2 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 6 1 0.27
Glioblastoma multiforme No 2 1 0.26
Hepatocarcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence