Top
GP5 has not been detected as a mutational cancer driver

GP5
Ensembl id ENSG00000178732
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GP5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 6 1.63
Lung squamous cell carcinoma No 4 4 2.30
Head and neck squamous cell carcinoma No 4 3 0.80
Prostate adenocarcinoma No 3 2 0.82
Lung adenocarcinoma No 4 2 0.51
Uterine corpus endometrioid carcinoma No 2 2 0.87
Colorectal adenocarcinoma No 4 2 0.87
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 3 1 0.09
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 4 1 0.62
Small cell lung carcinoma No 1 1 1.45
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence