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GON4L has not been detected as a mutational cancer driver

GON4L
Ensembl id ENSG00000116580
Mutated samples
Coding Sequence 122 (1.8%)
Protein Affecting 84 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GON4L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 18 4.88
Breast carcinoma No 13 10 0.87
Uterine corpus endometrioid carcinoma No 10 9 3.91
Lung squamous cell carcinoma No 9 8 4.60
Renal clear cell carcinoma No 11 6 1.44
Lung adenocarcinoma No 7 5 1.28
Serous ovarian adenocarcinoma No 7 5 1.58
Stomach adenocarcinoma No 7 5 3.11
Head and neck squamous cell carcinoma No 7 5 1.33
Bladder carcinoma No 6 4 4.08
Thyroid carcinoma No 2 2 0.62
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 7 2 1.37
Medulloblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 2 1 0.34
Multiple myeloma No 1 1 1.45
Hepatocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence