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GNPAT has not been detected as a mutational cancer driver

GNPAT
Ensembl id ENSG00000116906
Mutated samples
Coding Sequence 50 (0.7%)
Protein Affecting 29 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GNPAT gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 8 5 0.44
Cutaneous melanoma No 7 4 1.08
Serous ovarian adenocarcinoma No 4 4 1.27
Lung adenocarcinoma No 5 2 0.51
Lung squamous cell carcinoma No 3 2 1.15
Thyroid carcinoma No 2 2 0.62
Uterine corpus endometrioid carcinoma No 4 2 0.87
Head and neck squamous cell carcinoma No 4 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Non small cell lung carcinoma No 1 1 3.23
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 5 1 0.62
Esophageal carcinoma No 1 1 0.68
Chronic lymphocytic leukemia No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence