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GNAI2 has not been detected as a mutational cancer driver

GNAI2
Ensembl id ENSG00000114353
Mutated samples
Coding Sequence 35 (0.5%)
Protein Affecting 20 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GNAI2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 11 6 1.63
Breast carcinoma No 3 2 0.17
Renal clear cell carcinoma No 3 2 0.48
Uterine corpus endometrioid carcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Acute myeloid leukemia No 1 1 0.51
Serous ovarian adenocarcinoma No 1 1 0.32
Diffuse B cell lymphoma No 1 1 4.35
Esophageal carcinoma No 2 1 0.68
Medulloblastoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence