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GLB1L has not been detected as a mutational cancer driver

GLB1L
Ensembl id ENSG00000163521
Mutated samples
Coding Sequence 71 (1.0%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GLB1L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 5 1.36
Breast carcinoma No 4 2 0.17
Renal clear cell carcinoma No 2 2 0.48
Uterine corpus endometrioid carcinoma No 6 2 0.87
Head and neck squamous cell carcinoma No 9 2 0.53
Lung adenocarcinoma No 6 1 0.26
Lung squamous cell carcinoma No 6 1 0.57
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 3 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Stomach adenocarcinoma No 4 1 0.62
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Bladder carcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence