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GIPC2 has not been detected as a mutational cancer driver

GIPC2
Ensembl id ENSG00000137960
Mutated samples
Coding Sequence 59 (0.9%)
Protein Affecting 19 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GIPC2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 5 1.36
Uterine corpus endometrioid carcinoma No 4 3 1.30
Lung adenocarcinoma No 5 2 0.51
Lung squamous cell carcinoma No 4 2 1.15
Breast carcinoma No 4 1 0.09
Renal clear cell carcinoma No 5 1 0.24
Serous ovarian adenocarcinoma No 2 1 0.32
Small cell lung carcinoma No 2 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Head and neck squamous cell carcinoma No 5 1 0.27
Glioblastoma multiforme No 3 1 0.26
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Stomach adenocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence