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GCSAM has not been detected as a mutational cancer driver

GCSAM
Ensembl id ENSG00000174500
Mutated samples
Coding Sequence 25 (0.4%)
Protein Affecting 10 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GCSAM gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 2 2 1.15
Cutaneous melanoma No 7 2 0.54
Uterine corpus endometrioid carcinoma No 2 2 0.87
Glioblastoma multiforme No 3 2 0.53
Bladder carcinoma No 1 1 1.02
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 4 0 0.00
Breast carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence