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GABRG1 has not been detected as a mutational cancer driver

GABRG1
Ensembl id ENSG00000163285
Mutated samples
Coding Sequence 138 (2.0%)
Protein Affecting 95 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GABRG1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 44 31 8.40
Lung squamous cell carcinoma No 16 12 6.90
Lung adenocarcinoma No 17 11 2.81
Head and neck squamous cell carcinoma No 7 6 1.60
Prostate adenocarcinoma No 4 4 1.65
Colorectal adenocarcinoma No 5 4 1.75
Esophageal carcinoma No 4 4 2.74
Hepatocarcinoma No 4 3 3.33
Bladder carcinoma No 3 3 3.06
Breast carcinoma No 4 3 0.26
Small cell lung carcinoma No 3 3 4.35
Renal clear cell carcinoma No 3 2 0.48
Uterine corpus endometrioid carcinoma No 3 2 0.87
Glioblastoma multiforme No 2 2 0.53
Neuroblastoma No 3 1 0.48
Non small cell lung carcinoma No 2 1 3.23
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Chronic lymphocytic leukemia No 6 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Stomach adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence