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GABRB1 has not been detected as a mutational cancer driver

GABRB1
Ensembl id ENSG00000163288
Mutated samples
Coding Sequence 108 (1.6%)
Protein Affecting 69 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GABRB1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 37 22 5.96
Lung adenocarcinoma No 11 9 2.30
Head and neck squamous cell carcinoma No 5 5 1.33
Lung squamous cell carcinoma No 6 4 2.30
Stomach adenocarcinoma No 5 4 2.48
Esophageal carcinoma No 5 4 2.74
Prostate adenocarcinoma No 3 3 1.23
Renal clear cell carcinoma No 3 3 0.72
Small cell lung carcinoma No 3 3 4.35
Bladder carcinoma No 3 2 2.04
Uterine corpus endometrioid carcinoma No 5 2 0.87
Lower grade glioma No 2 2 1.18
Serous ovarian adenocarcinoma No 2 2 0.63
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 2 1 0.09
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 2 1 0.26
Chronic lymphocytic leukemia No 10 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence