G3BP2 mutations in 10 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Prostate adenocarcinoma, Lung adenocarcinoma, Bladder carcinoma, Breast carcinoma, Lung squamous cell carcinoma, Renal clear cell carcinoma, Cutaneous melanoma, Uterine corpus endometrioid carcinoma, Stomach adenocarcinoma, Head and neck squamous cell carcinoma

Ensembl id ENSG00000138757
Mutated samples
Coding Sequence 34 (0.5%)
Protein Affecting 28 (0.4%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all G3BP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma Yes 4 4 0.35
Bladder carcinoma Yes 3 3 3.06
Lung squamous cell carcinoma Yes 4 3 1.72
Cutaneous melanoma Yes 6 3 0.81
Uterine corpus endometrioid carcinoma Yes 3 3 1.30
Head and neck squamous cell carcinoma Yes 3 3 0.80
Prostate adenocarcinoma Yes 2 2 0.82
Lung adenocarcinoma Yes 2 2 0.51
Renal clear cell carcinoma Yes 2 2 0.48
Stomach adenocarcinoma Yes 4 2 1.24
Glioblastoma multiforme No 1 1 0.26
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence