Top
FSTL5 has not been detected as a mutational cancer driver

FSTL5
Ensembl id ENSG00000168843
Mutated samples
Coding Sequence 188 (2.8%)
Protein Affecting 118 (1.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FSTL5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 34 27 7.32
Lung adenocarcinoma No 24 21 5.37
Head and neck squamous cell carcinoma No 15 11 2.93
Lung squamous cell carcinoma No 12 9 5.17
Stomach adenocarcinoma No 12 8 4.97
Esophageal carcinoma No 16 8 5.48
Breast carcinoma No 7 7 0.61
Colorectal adenocarcinoma No 5 5 2.18
Lower grade glioma No 5 4 2.37
Uterine corpus endometrioid carcinoma No 4 3 1.30
Serous ovarian adenocarcinoma No 3 3 0.95
Small cell lung carcinoma No 3 3 4.35
Bladder carcinoma No 3 2 2.04
Glioblastoma multiforme No 6 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 2 1 0.47
Non small cell lung carcinoma No 2 1 3.23
Chronic lymphocytic leukemia No 21 1 0.34
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Pylocytic astrocytoma No 8 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence