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FSHR has not been detected as a mutational cancer driver

FSHR
Ensembl id ENSG00000170820
Mutated samples
Coding Sequence 136 (2.0%)
Protein Affecting 91 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FSHR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 38 22 5.96
Lung adenocarcinoma No 21 17 4.35
Lung squamous cell carcinoma No 18 14 8.05
Stomach adenocarcinoma No 11 8 4.97
Head and neck squamous cell carcinoma No 8 7 1.87
Esophageal carcinoma No 9 5 3.42
Breast carcinoma No 4 4 0.35
Serous ovarian adenocarcinoma No 4 4 1.27
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 3 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Uterine corpus endometrioid carcinoma No 4 1 0.43
Chronic lymphocytic leukemia No 7 1 0.34
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Non small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence