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FRMD4B has not been detected as a mutational cancer driver

FRMD4B
Ensembl id ENSG00000114541
Mutated samples
Coding Sequence 57 (0.8%)
Protein Affecting 32 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FRMD4B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 26 16 4.34
Breast carcinoma No 2 2 0.17
Serous ovarian adenocarcinoma No 3 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 1 1 0.48
Lung squamous cell carcinoma No 2 1 0.57
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Lower grade glioma No 1 1 0.59
Colorectal adenocarcinoma No 2 1 0.44
Head and neck squamous cell carcinoma No 1 1 0.27
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 4 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence