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FOSL2 has not been detected as a mutational cancer driver

FOSL2
Ensembl id ENSG00000075426
Mutated samples
Coding Sequence 33 (0.5%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FOSL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 7 7 1.87
Cutaneous melanoma No 9 4 1.08
Bladder carcinoma No 2 2 2.04
Breast carcinoma No 3 2 0.17
Uterine corpus endometrioid carcinoma No 2 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Lung adenocarcinoma No 2 1 0.26
Lung squamous cell carcinoma No 1 1 0.57
Neuroblastoma No 1 1 0.48
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Stomach adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence