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FMO3 has not been detected as a mutational cancer driver

FMO3
Ensembl id ENSG00000007933
Mutated samples
Coding Sequence 64 (0.9%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FMO3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 30 19 5.15
Lung adenocarcinoma No 6 5 1.28
Bladder carcinoma No 6 5 5.10
Stomach adenocarcinoma No 4 3 1.86
Lung squamous cell carcinoma No 3 2 1.15
Head and neck squamous cell carcinoma No 3 2 0.53
Glioblastoma multiforme No 3 2 0.53
Esophageal carcinoma No 2 2 1.37
Breast carcinoma No 2 1 0.09
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 1 1 0.43
Colorectal adenocarcinoma No 2 1 0.44
Pancreas adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence