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FMNL2 has not been detected as a mutational cancer driver

FMNL2
Ensembl id ENSG00000157827
Mutated samples
Coding Sequence 76 (1.1%)
Protein Affecting 38 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FMNL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 25 17 4.61
Breast carcinoma No 6 5 0.44
Stomach adenocarcinoma No 5 3 1.86
Glioblastoma multiforme No 3 3 0.79
Lung adenocarcinoma No 3 2 0.51
Hepatocarcinoma No 9 2 2.22
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Uterine corpus endometrioid carcinoma No 1 1 0.43
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 4 1 0.27
Renal clear cell carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 9 0 0.00
Lower grade glioma No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence