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FMN2 has not been detected as a mutational cancer driver

FMN2
Ensembl id ENSG00000155816
Mutated samples
Coding Sequence 328 (4.8%)
Protein Affecting 209 (3.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FMN2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 104 58 15.72
Lung adenocarcinoma No 30 26 6.65
Head and neck squamous cell carcinoma No 31 25 6.67
Lung squamous cell carcinoma No 29 22 12.64
Breast carcinoma No 19 16 1.39
Stomach adenocarcinoma No 19 13 8.07
Uterine corpus endometrioid carcinoma No 10 9 3.91
Esophageal carcinoma No 13 8 5.48
Small cell lung carcinoma No 6 6 8.70
Renal clear cell carcinoma No 9 5 1.20
Colorectal adenocarcinoma No 5 5 2.18
Bladder carcinoma No 4 4 4.08
Serous ovarian adenocarcinoma No 6 3 0.95
Prostate adenocarcinoma No 5 2 0.82
Pancreas adenocarcinoma No 4 2 0.93
Non small cell lung carcinoma No 6 2 6.45
Medulloblastoma No 1 1 0.48
Neuroblastoma No 4 1 0.48
Lower grade glioma No 4 1 0.59
Hepatocarcinoma No 3 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 12 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence