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FLNB has not been detected as a mutational cancer driver

FLNB
Ensembl id ENSG00000136068
Mutated samples
Coding Sequence 162 (2.4%)
Protein Affecting 112 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FLNB gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 66 42 11.38
Breast carcinoma No 18 15 1.31
Uterine corpus endometrioid carcinoma No 10 9 3.91
Lung adenocarcinoma No 11 8 2.05
Head and neck squamous cell carcinoma No 8 6 1.60
Lower grade glioma No 4 4 2.37
Bladder carcinoma No 6 3 3.06
Renal clear cell carcinoma No 4 3 0.72
Chronic lymphocytic leukemia No 5 3 1.03
Serous ovarian adenocarcinoma No 4 3 0.95
Stomach adenocarcinoma No 6 3 1.86
Glioblastoma multiforme No 4 3 0.79
Hepatocarcinoma No 4 2 2.22
Lung squamous cell carcinoma No 4 2 1.15
Colorectal adenocarcinoma No 2 2 0.87
Esophageal carcinoma No 2 2 1.37
Neuroblastoma No 1 1 0.48
Multiple myeloma No 1 1 1.45
Prostate adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence