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FILIP1L has not been detected as a mutational cancer driver

FILIP1L
Ensembl id ENSG00000168386
Mutated samples
Coding Sequence 61 (0.9%)
Protein Affecting 40 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FILIP1L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 12 3.25
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 5 4 2.30
Stomach adenocarcinoma No 4 4 2.48
Head and neck squamous cell carcinoma No 5 4 1.07
Esophageal carcinoma No 3 3 2.05
Prostate adenocarcinoma No 2 2 0.82
Thyroid carcinoma No 3 2 0.62
Lung adenocarcinoma No 2 1 0.26
Bladder carcinoma No 2 1 1.02
Uterine corpus endometrioid carcinoma No 1 1 0.43
Chronic lymphocytic leukemia No 4 1 0.34
Serous ovarian adenocarcinoma No 1 1 0.32
Renal clear cell carcinoma No 1 0 0.00
Pylocytic astrocytoma No 3 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence