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FGD5 has not been detected as a mutational cancer driver

FGD5
Ensembl id ENSG00000154783
Mutated samples
Coding Sequence 116 (1.7%)
Protein Affecting 75 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FGD5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 34 24 6.50
Lung adenocarcinoma No 16 10 2.56
Glioblastoma multiforme No 13 7 1.85
Breast carcinoma No 7 5 0.44
Lung squamous cell carcinoma No 5 4 2.30
Renal clear cell carcinoma No 4 3 0.72
Serous ovarian adenocarcinoma No 3 3 0.95
Head and neck squamous cell carcinoma No 4 3 0.80
Prostate adenocarcinoma No 2 2 0.82
Bladder carcinoma No 4 2 2.04
Uterine corpus endometrioid carcinoma No 4 2 0.87
Lower grade glioma No 4 2 1.18
Stomach adenocarcinoma No 3 2 1.24
Colorectal adenocarcinoma No 3 2 0.87
Thyroid carcinoma No 2 1 0.31
Chronic lymphocytic leukemia No 2 1 0.34
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 3 1 0.68
Medulloblastoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence