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FCRL3 has not been detected as a mutational cancer driver

FCRL3
Ensembl id ENSG00000160856
Mutated samples
Coding Sequence 127 (1.9%)
Protein Affecting 75 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FCRL3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 35 23 6.23
Lung adenocarcinoma No 14 9 2.30
Stomach adenocarcinoma No 8 8 4.97
Lung squamous cell carcinoma No 13 7 4.02
Head and neck squamous cell carcinoma No 10 6 1.60
Breast carcinoma No 9 5 0.44
Uterine corpus endometrioid carcinoma No 6 5 2.17
Small cell lung carcinoma No 4 3 4.35
Serous ovarian adenocarcinoma No 3 2 0.63
Colorectal adenocarcinoma No 4 2 0.87
Esophageal carcinoma No 7 2 1.37
Hepatocarcinoma No 5 1 1.11
Neuroblastoma No 1 1 0.48
Lower grade glioma No 3 1 0.59
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence