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FBXO8 has not been detected as a mutational cancer driver

FBXO8
Ensembl id ENSG00000164117
Mutated samples
Coding Sequence 20 (0.3%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FBXO8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 4 2 0.17
Stomach adenocarcinoma No 2 2 1.24
Head and neck squamous cell carcinoma No 3 2 0.53
Bladder carcinoma No 1 1 1.02
Lung squamous cell carcinoma No 1 1 0.57
Cutaneous melanoma No 2 1 0.27
Uterine corpus endometrioid carcinoma No 1 1 0.43
Glioblastoma multiforme No 2 1 0.26
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence