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FBXO11 is detected as a mutational cancer driver in 1 cancer type: Diffuse B cell lymphoma

FBXO11
Ensembl id ENSG00000138081
Mutated samples
Coding Sequence 131 (1.9%)
Protein Affecting 50 (0.7%)
Mode of action Unclassified
Known driver Yes
Cancer type Signals (Biases)
DLBC F
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FBXO11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Diffuse B cell lymphoma Yes 6 5 21.74
Cutaneous melanoma No 27 9 2.44
Head and neck squamous cell carcinoma No 8 7 1.87
Lung squamous cell carcinoma No 8 5 2.87
Esophageal carcinoma No 6 4 2.74
Breast carcinoma No 10 3 0.26
Stomach adenocarcinoma No 10 3 1.86
Lung adenocarcinoma No 14 2 0.51
Thyroid carcinoma No 2 2 0.62
Uterine corpus endometrioid carcinoma No 7 2 0.87
Colorectal adenocarcinoma No 5 2 0.87
Hepatocarcinoma No 5 1 1.11
Bladder carcinoma No 1 1 1.02
Acute myeloid leukemia No 2 1 0.51
Renal clear cell carcinoma No 6 1 0.24
Neuroblastoma No 2 1 0.48
Small cell lung carcinoma No 3 1 1.45
Prostate adenocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence