Top
IntOGen
FAT4 × Acute Myeloid Leukemia ×

FAT4 is detected as a mutational cancer driver in Acute Myeloid Leukemia

FAT4 reports in Acute Myeloid Leukemia (AML)

Cancer type details
Acute Myeloid Leukemia
Cohorts 9
Samples 661
Mutations 295,755
Driver genes 62
Gene details
FAT4
Ensembl ID ENSG00000196159
Transcript ID ENST00000674496
Protein ID ENSP00000501473
Cohorts where is driver 1
Mutated samples 3
Mutated samples (%) 0.45
Mutations 5
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence