IntOGen - FANCC gene cancer mutations

FANCC is detected as a mutational cancer driver

FANCC reports

Methods
Mutation distribution

Gene details

FANCC
Ensembl ID ENSG00000158169 Transcript ID ENST00000289081 Protein ID ENSP00000289081
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 2 Mutations 150
Mode of action Activating
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence