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FAM208A has not been detected as a mutational cancer driver

FAM208A
Ensembl id ENSG00000163946
Mutated samples
Coding Sequence 78 (1.1%)
Protein Affecting 48 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FAM208A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 10 6 0.52
Cutaneous melanoma No 12 5 1.36
Head and neck squamous cell carcinoma No 7 5 1.33
Lung adenocarcinoma No 7 4 1.02
Renal clear cell carcinoma No 4 4 0.96
Uterine corpus endometrioid carcinoma No 5 4 1.74
Stomach adenocarcinoma No 9 4 2.48
Bladder carcinoma No 3 3 3.06
Lung squamous cell carcinoma No 5 3 1.72
Serous ovarian adenocarcinoma No 3 3 0.95
Esophageal carcinoma No 3 3 2.05
Small cell lung carcinoma No 2 2 2.90
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 2 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence