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EYA3 has not been detected as a mutational cancer driver

EYA3
Ensembl id ENSG00000158161
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EYA3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 7 7 1.90
Lung adenocarcinoma No 3 3 0.77
Breast carcinoma No 4 3 0.26
Head and neck squamous cell carcinoma No 5 3 0.80
Lung squamous cell carcinoma No 3 2 1.15
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 1 1 1.02
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Esophageal carcinoma No 2 1 0.68
Hepatocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence