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ERCC2 × Bladder Urothelial Carcinoma ×

ERCC2 is detected as a mutational cancer driver in Bladder Urothelial Carcinoma

ERCC2 reports in Bladder Urothelial Carcinoma (BLCA)

Cancer type details
Bladder Urothelial Carcinoma
Cohorts 8
Samples 905
Mutations 6,585,575
Driver genes 89
Gene details
ERCC2
Ensembl ID ENSG00000104884
Transcript ID ENST00000391945
Protein ID ENSP00000375809
Cohorts where is driver 6
Mutated samples 75
Mutated samples (%) 8.29
Mutations 84
Mode of action Activating
Known driver False
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence