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ERC2 has not been detected as a mutational cancer driver

ERC2
Ensembl id ENSG00000187672
Mutated samples
Coding Sequence 143 (2.1%)
Protein Affecting 90 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ERC2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 68 49 13.28
Head and neck squamous cell carcinoma No 8 7 1.87
Lung adenocarcinoma No 7 6 1.53
Esophageal carcinoma No 7 6 4.11
Bladder carcinoma No 5 4 4.08
Breast carcinoma No 4 4 0.35
Stomach adenocarcinoma No 10 4 2.48
Lung squamous cell carcinoma No 3 2 1.15
Chronic lymphocytic leukemia No 14 2 0.69
Glioblastoma multiforme No 3 2 0.53
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 2 1 0.43
Serous ovarian adenocarcinoma No 2 1 0.32
Acute lymphocytic leukemia No 3 1 0.82
Prostate adenocarcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence