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ENAM has not been detected as a mutational cancer driver

ENAM
Ensembl id ENSG00000132464
Mutated samples
Coding Sequence 148 (2.2%)
Protein Affecting 93 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ENAM gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 55 42 11.38
Lung squamous cell carcinoma No 14 10 5.75
Lung adenocarcinoma No 12 9 2.30
Breast carcinoma No 11 7 0.61
Head and neck squamous cell carcinoma No 9 6 1.60
Uterine corpus endometrioid carcinoma No 9 3 1.30
Serous ovarian adenocarcinoma No 4 3 0.95
Stomach adenocarcinoma No 5 3 1.86
Glioblastoma multiforme No 5 3 0.79
Lower grade glioma No 4 2 1.18
Small cell lung carcinoma No 3 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Renal clear cell carcinoma No 4 1 0.24
Prostate adenocarcinoma No 3 0 0.00
Hepatocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Multiple myeloma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence