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EML6 has not been detected as a mutational cancer driver

EML6
Ensembl id ENSG00000214595
Mutated samples
Coding Sequence 31 (0.5%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EML6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 7 5 0.44
Renal clear cell carcinoma No 3 3 0.72
Medulloblastoma No 3 2 0.95
Uterine corpus endometrioid carcinoma No 7 2 0.87
Pancreas adenocarcinoma No 1 1 0.47
Stomach adenocarcinoma No 1 1 0.62
Hepatocarcinoma No 4 0 0.00
Cutaneous melanoma No 2 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence