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EIF4E2 has not been detected as a mutational cancer driver

EIF4E2
Ensembl id ENSG00000135930
Mutated samples
Coding Sequence 27 (0.4%)
Protein Affecting 13 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EIF4E2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 2 2 0.51
Cutaneous melanoma No 5 2 0.54
Uterine corpus endometrioid carcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Breast carcinoma No 1 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Hepatocarcinoma No 5 0 0.00
Bladder carcinoma No 1 0 0.00
Lung squamous cell carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence