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EFHB has not been detected as a mutational cancer driver

EFHB
Ensembl id ENSG00000163576
Mutated samples
Coding Sequence 72 (1.1%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EFHB gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 32 27 7.32
Lung adenocarcinoma No 8 8 2.05
Breast carcinoma No 5 5 0.44
Bladder carcinoma No 4 3 3.06
Lung squamous cell carcinoma No 5 3 1.72
Uterine corpus endometrioid carcinoma No 2 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Head and neck squamous cell carcinoma No 2 2 0.53
Esophageal carcinoma No 3 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Renal clear cell carcinoma No 1 1 0.24
Multiple myeloma No 2 1 1.45
Glioblastoma multiforme No 1 1 0.26
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Stomach adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence