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EEF1B2 is detected as a mutational cancer driver in 1 cancer type: Prostate adenocarcinoma and in the PAN-cancer analysis

EEF1B2
Ensembl id ENSG00000114942
Mutated samples
Coding Sequence 35 (0.5%)
Protein Affecting 25 (0.4%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
PRAD C
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EEF1B2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Prostate adenocarcinoma Yes 5 5 2.06
Lung adenocarcinoma Yes 4 4 1.02
Bladder carcinoma Yes 2 2 2.04
Lower grade glioma Yes 2 2 1.18
Cutaneous melanoma No 13 7 1.90
Breast carcinoma No 2 2 0.17
Lung squamous cell carcinoma No 2 1 0.57
Uterine corpus endometrioid carcinoma No 2 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Hepatocarcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence