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ECE1 has not been detected as a mutational cancer driver

ECE1
Ensembl id ENSG00000117298
Mutated samples
Coding Sequence 60 (0.9%)
Protein Affecting 41 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ECE1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 14 3.79
Uterine corpus endometrioid carcinoma No 6 5 2.17
Breast carcinoma No 5 4 0.35
Stomach adenocarcinoma No 4 3 1.86
Lung adenocarcinoma No 3 2 0.51
Serous ovarian adenocarcinoma No 2 2 0.63
Colorectal adenocarcinoma No 3 2 0.87
Head and neck squamous cell carcinoma No 4 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 2 1 0.68
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence