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DYSF has not been detected as a mutational cancer driver

DYSF
Ensembl id ENSG00000135636
Mutated samples
Coding Sequence 241 (3.5%)
Protein Affecting 157 (2.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DYSF gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 85 49 13.28
Lung adenocarcinoma No 27 15 3.84
Lung squamous cell carcinoma No 20 15 8.62
Stomach adenocarcinoma No 16 13 8.07
Breast carcinoma No 13 11 0.96
Uterine corpus endometrioid carcinoma No 10 9 3.91
Head and neck squamous cell carcinoma No 14 9 2.40
Esophageal carcinoma No 9 7 4.79
Colorectal adenocarcinoma No 7 5 2.18
Glioblastoma multiforme No 5 5 1.32
Bladder carcinoma No 5 4 4.08
Renal clear cell carcinoma No 6 3 0.72
Non small cell lung carcinoma No 5 3 9.68
Serous ovarian adenocarcinoma No 3 3 0.95
Small cell lung carcinoma No 3 3 4.35
Hepatocarcinoma No 1 1 1.11
Acute myeloid leukemia No 3 1 0.51
Diffuse B cell lymphoma No 1 1 4.35
Pancreas adenocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence