IntOGen - DUSP16 gene cancer mutations

DUSP16 is detected as a mutational cancer driver

DUSP16 reports

Methods
Mutation distribution

Gene details

DUSP16
Ensembl ID ENSG00000111266 Transcript ID ENST00000298573 Protein ID ENSP00000298573
Cancer types where is driver 1 Cohorts where is driver 2 Mutated samples 10 Mutations 218
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence