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DRD5 has not been detected as a mutational cancer driver

DRD5
Ensembl id ENSG00000169676
Mutated samples
Coding Sequence 113 (1.7%)
Protein Affecting 74 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DRD5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 39 23 6.23
Glioblastoma multiforme No 10 9 2.37
Lung adenocarcinoma No 12 8 2.05
Head and neck squamous cell carcinoma No 9 7 1.87
Stomach adenocarcinoma No 7 6 3.73
Uterine corpus endometrioid carcinoma No 5 4 1.74
Esophageal carcinoma No 4 4 2.74
Lung squamous cell carcinoma No 6 3 1.72
Breast carcinoma No 3 2 0.17
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 3 2 0.87
Prostate adenocarcinoma No 2 1 0.41
Renal clear cell carcinoma No 3 1 0.24
Multiple myeloma No 3 1 1.45
Lower grade glioma No 2 1 0.59
Bladder carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence