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DPP10 has not been detected as a mutational cancer driver

DPP10
Ensembl id ENSG00000175497
Mutated samples
Coding Sequence 210 (3.1%)
Protein Affecting 133 (2.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DPP10 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 45 31 8.40
Lung adenocarcinoma No 19 17 4.35
Head and neck squamous cell carcinoma No 18 15 4.00
Lung squamous cell carcinoma No 19 14 8.05
Esophageal carcinoma No 10 8 5.48
Breast carcinoma No 8 7 0.61
Glioblastoma multiforme No 9 7 1.85
Colorectal adenocarcinoma No 9 6 2.62
Serous ovarian adenocarcinoma No 6 5 1.58
Stomach adenocarcinoma No 6 4 2.48
Renal clear cell carcinoma No 5 3 0.72
Neuroblastoma No 3 3 1.43
Small cell lung carcinoma No 3 3 4.35
Prostate adenocarcinoma No 2 2 0.82
Bladder carcinoma No 3 2 2.04
Non small cell lung carcinoma No 4 2 6.45
Hepatocarcinoma No 5 1 1.11
Uterine corpus endometrioid carcinoma No 2 1 0.43
Multiple myeloma No 2 1 1.45
Lower grade glioma No 1 1 0.59
Medulloblastoma No 2 0 0.00
Chronic lymphocytic leukemia No 21 0 0.00
Pylocytic astrocytoma No 6 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence