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DNER has not been detected as a mutational cancer driver

DNER
Ensembl id ENSG00000187957
Mutated samples
Coding Sequence 101 (1.5%)
Protein Affecting 75 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DNER gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 35 22 5.96
Lung adenocarcinoma No 11 9 2.30
Uterine corpus endometrioid carcinoma No 8 8 3.48
Small cell lung carcinoma No 5 5 7.25
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 5 4 2.30
Stomach adenocarcinoma No 6 4 2.48
Bladder carcinoma No 3 3 3.06
Esophageal carcinoma No 3 3 2.05
Hepatocarcinoma No 3 2 2.22
Renal clear cell carcinoma No 2 2 0.48
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Chronic lymphocytic leukemia No 6 1 0.34
Multiple myeloma No 2 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Diffuse B cell lymphoma No 1 1 4.35
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence