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DNAJC6 has not been detected as a mutational cancer driver

DNAJC6
Ensembl id ENSG00000116675
Mutated samples
Coding Sequence 72 (1.1%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DNAJC6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 21 14 3.79
Lung adenocarcinoma No 12 10 2.56
Breast carcinoma No 6 6 0.52
Lung squamous cell carcinoma No 7 6 3.45
Stomach adenocarcinoma No 5 4 2.48
Small cell lung carcinoma No 2 2 2.90
Head and neck squamous cell carcinoma No 2 2 0.53
Glioblastoma multiforme No 2 2 0.53
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 2 1 0.48
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 1 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 2 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence