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DNAJC13 has not been detected as a mutational cancer driver

DNAJC13
Ensembl id ENSG00000138246
Mutated samples
Coding Sequence 101 (1.5%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DNAJC13 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 20 16 4.34
Breast carcinoma No 14 11 0.96
Lung squamous cell carcinoma No 13 8 4.60
Lung adenocarcinoma No 7 7 1.79
Head and neck squamous cell carcinoma No 7 6 1.60
Bladder carcinoma No 7 5 5.10
Uterine corpus endometrioid carcinoma No 5 4 1.74
Colorectal adenocarcinoma No 4 4 1.75
Prostate adenocarcinoma No 3 3 1.23
Stomach adenocarcinoma No 4 3 1.86
Hepatocarcinoma No 2 2 2.22
Pancreas adenocarcinoma No 2 1 0.47
Renal clear cell carcinoma No 3 1 0.24
Thyroid carcinoma No 1 1 0.31
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 3 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Non small cell lung carcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence