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DNAH7 has not been detected as a mutational cancer driver

DNAH7
Ensembl id ENSG00000118997
Mutated samples
Coding Sequence 396 (5.8%)
Protein Affecting 309 (4.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DNAH7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 145 119 32.25
Head and neck squamous cell carcinoma No 31 27 7.20
Lung squamous cell carcinoma No 34 26 14.94
Lung adenocarcinoma No 31 24 6.14
Stomach adenocarcinoma No 33 23 14.29
Breast carcinoma No 17 13 1.13
Small cell lung carcinoma No 13 13 18.84
Uterine corpus endometrioid carcinoma No 15 12 5.22
Renal clear cell carcinoma No 12 10 2.40
Bladder carcinoma No 11 8 8.16
Esophageal carcinoma No 9 8 5.48
Glioblastoma multiforme No 8 6 1.58
Prostate adenocarcinoma No 3 3 1.23
Hepatocarcinoma No 11 3 3.33
Lower grade glioma No 4 3 1.78
Chronic lymphocytic leukemia No 3 2 0.69
Serous ovarian adenocarcinoma No 4 2 0.63
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 2 1 3.23
Multiple myeloma No 3 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Diffuse B cell lymphoma No 1 1 4.35
Acute lymphocytic leukemia No 1 1 0.82
Neuroblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence