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DNAH12 has not been detected as a mutational cancer driver

DNAH12
Ensembl id ENSG00000174844
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 48 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DNAH12 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 13 3.52
Breast carcinoma No 14 12 1.05
Uterine corpus endometrioid carcinoma No 7 5 2.17
Lung squamous cell carcinoma No 5 4 2.30
Renal clear cell carcinoma No 3 3 0.72
Lung adenocarcinoma No 2 2 0.51
Hepatocarcinoma No 4 2 2.22
Glioblastoma multiforme No 3 2 0.53
Pancreas adenocarcinoma No 1 1 0.47
Stomach adenocarcinoma No 2 1 0.62
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 1 1 0.27
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence