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DNAH1 has not been detected as a mutational cancer driver

DNAH1
Ensembl id ENSG00000114841
Mutated samples
Coding Sequence 234 (3.4%)
Protein Affecting 133 (2.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DNAH1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 73 36 9.76
Uterine corpus endometrioid carcinoma No 19 11 4.78
Lung adenocarcinoma No 17 10 2.56
Breast carcinoma No 18 10 0.87
Bladder carcinoma No 12 9 9.18
Serous ovarian adenocarcinoma No 8 7 2.22
Stomach adenocarcinoma No 12 7 4.35
Glioblastoma multiforme No 8 6 1.58
Lung squamous cell carcinoma No 8 5 2.87
Renal clear cell carcinoma No 18 5 1.20
Head and neck squamous cell carcinoma No 10 5 1.33
Esophageal carcinoma No 6 5 3.42
Thyroid carcinoma No 4 4 1.24
Prostate adenocarcinoma No 6 3 1.23
Neuroblastoma No 3 3 1.43
Medulloblastoma No 3 2 0.95
Lower grade glioma No 3 2 1.18
Hepatocarcinoma No 1 1 1.11
Colorectal adenocarcinoma No 1 1 0.44
Diffuse B cell lymphoma No 1 1 4.35
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence