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DHRS3 has not been detected as a mutational cancer driver

DHRS3
Ensembl id ENSG00000162496
Mutated samples
Coding Sequence 25 (0.4%)
Protein Affecting 10 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DHRS3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 5 1.36
Breast carcinoma No 2 2 0.17
Lung adenocarcinoma No 1 1 0.26
Multiple myeloma No 1 1 1.45
Stomach adenocarcinoma No 1 1 0.62
Hepatocarcinoma No 2 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence