DFFA has not been detected as a mutational cancer driver

Ensembl id ENSG00000160049
Mutated samples
Coding Sequence 17 (0.3%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DFFA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Bladder carcinoma No 3 3 3.06
Lung adenocarcinoma No 2 2 0.51
Prostate adenocarcinoma No 1 1 0.41
Breast carcinoma No 1 1 0.09
Cutaneous melanoma No 1 1 0.27
Stomach adenocarcinoma No 2 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Diffuse B cell lymphoma No 2 1 4.35
Hepatocarcinoma No 2 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence