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DCAF8 has not been detected as a mutational cancer driver

DCAF8
Ensembl id ENSG00000132716
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DCAF8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 6 1.53
Cutaneous melanoma No 14 4 1.08
Uterine corpus endometrioid carcinoma No 8 4 1.74
Lung squamous cell carcinoma No 4 3 1.72
Stomach adenocarcinoma No 6 3 1.86
Head and neck squamous cell carcinoma No 6 3 0.80
Breast carcinoma No 4 2 0.17
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Acute myeloid leukemia No 1 1 0.51
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 2 1 0.26
Hepatocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence